BBS8 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12505-1-AP

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Con: 53 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse testis tissue, human lung tissue, NIH/3T3 cells

Positive IP detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
tetratricopeptide repeat domain 8

Calculated molecular weight:
531aa,60 kDa

Observed molecular weight:
50-52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

BBS8, TPR repeat protein 8, TTC8

BBS8 (also known as TTC8) is a subunit of BBSome complex which is necessary for ciliary membrane biogenesis. BBS8 localizes specifically to ciliated structures, such as the connecting cilium of the retina and columnar epithelial cells in the lung. Defects in BBS8 cause Bardet-Biedl syndrome type 8 (BBS8), an genetic disorder characterised by retinal degeneration, obesity, polydactyly, cognitive impairment and kidney failure. BBS8 generates two alternatively spliced isoforms. Western blot analysis using this antibody detected a major band around 60 kD in lung tissue.

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