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  • KD/KO Validated

TWIST2 Polyclonal antibody

TWIST2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse





Cat no : 11752-1-AP


bHLHa39, Dermis expressed protein 1, Dermo 1, DERMO1, twist homolog 2 (Drosophila), Twist related protein 2, TWIST2

Tested Applications

Positive WB detected inNIH/3T3 cells, MCF-7 cells, mouse liver tissue

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11752-1-AP targets TWIST2 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TWIST2 fusion protein Ag2348
Full Name twist homolog 2 (Drosophila)
Calculated Molecular Weight 160 aa, 18 kDa
Observed Molecular Weight 21 kDa, 60 kDa
GenBank Accession NumberBC033168
Gene Symbol TWIST2
Gene ID (NCBI) 117581
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TWIST2, also named as BHLHA39 and DERMO1,is a basic helix-loop-helix protein which acts as a transcriptional regulator, plays a central role in differentiation of mesodermal during embryogenesis. TWIST2 inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors. It is also implicated in tumorigenesis, invasion and metastasis. TWIST2 forms both homodimers(45KD) and heterodimers with E2A E proteins, and dimer partner selection is a critical mediator of TWIST function. (PMID:14724576, 16502419).


Product Specific Protocols
WB protocol for TWIST2 antibody 11752-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Aging (Albany NY)

LINC01235-TWIST2 feedback loop facilitates epithelial-mesenchymal transition in gastric cancer by inhibiting THBS2.

Authors - Yu-En Tan

Front Cell Dev Biol

NR2F1-AS1/miR-190a/PHLDB2 Induces the Epithelial-Mesenchymal Transformation Process in Gastric Cancer by Promoting Phosphorylation of AKT3.

Authors - Jinqi Lv

Front Oncol

TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.

Authors - Rongkun Li


The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells.

Authors - Laurent Jacqueroud

J Cancer

Asymmetric Division Gene Neurl2 Mediates Twist2 Regulation of Self-Renewal of Mouse Lewis Lung Cancer Stem Cells.

Authors - Doudou Liu
  • KD Validated


Overexpression of NuSAP1 is predictive of an unfavourable prognosis and promotes proliferation and invasion of triple-negative breast cancer cells via the Wnt/β-catenin/EMT signalling axis.

Authors - Li Sun