USP36 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14783-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
Jurkat cells, HeLa cells, HepG2 cells, Jurkat cells

Positive IP detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ubiquitin specific peptidase 36

Calculated molecular weight:
1123aa,123 kDa

Observed molecular weight:
100-123 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
USP36

Synonyms
Deubiquitinating enzyme 36, DUB1, KIAA1453, Ubiquitin thiolesterase 36, USP36
Background

USP36(Ubiquitin carboxyl-terminal hydrolase 36) is also named as KIAA1453, FLJ12851, DUB1 and belongs to the peptidase C19 family. It regulates the transcription and processing of rRNA by deubiquitylating various proteins involved in these processes, and the aberrant nucleolar structure in its absence is secondary to deficient ribosome biogenesis. USP36 plays a crucial role in regulating the structure and function of nucleoli.(PMID:19208757). The ubiquitin-specific protease that is required in germline, epithelial, and intestinal stem cells(PMID:19039105). It has 2 isoforms produced by alternative splicing.


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