WEE1 Polyclonal antibody

WEE1 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14375-1-AP


WEE1, WEE1 homolog (S. pombe), Wee1 like protein kinase, WEE1A, Wee1A kinase, WEE1hu

Tested Applications

Recommended dilution

Sample-dependent, check data in validation data gallery

Product Information

14375-1-AP targets WEE1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen WEE1 fusion protein Ag5751
Full Name WEE1 homolog (S. pombe)
Calculated molecular weight 72 kDa
Observed molecular weight 72 kDa
GenBank accession numberBC051831
Gene symbol WEE1
Gene ID (NCBI) 7465
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

WEE1 kinase is a serine-threonine kinase that regulates G2/M checkpoint transition. WEE1 triggers G2/M arrest through inhibitory phosphorylation on Tyr15 of CDK1 (Cdc2) and preventing entry into mitosis to allow DNA repair during DNA damage (PMID: 27427153).The predicted native molecular weight for Wee1 based on the intact human Wee1 cDNA sequence is 72 kDa, whereas the 95-110 kDa protein is a highly modified product (PMID: 7568188). Others have shown that Wee1 is 70-72 kDa and 49-55 kDa (PMID: 12214061).



J Exp Med

WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathway.

Authors - Ensong Guo
  • KD Validated


miR-155 downregulates ErbB2 and suppresses ErbB2-induced malignant transformation of breast epithelial cells.

Authors - X-H He

Exp Cell Res

Cdc14a has a role in spermatogenesis, sperm maturation and male fertility.

Authors - Zongzhuang Wen

Exp Cell Res

NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.

Authors - Xin Zhao

Exp Cell Res

The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.

Authors - Pan Wei


The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.

Authors - Dao-Zhou Liu