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ZEB2 Polyclonal antibody

ZEB2 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human and More (3)





Cat no : 14026-1-AP


KIAA0569, SIP 1, SIP1, Smad interacting protein 1, SMADIP1, ZEB2, ZFHX1B, ZFX1B

Tested Applications

Positive WB detected inHEK-293 cells, SGC-7901 cells, HepG2 cells, A549 cells, Hela cells
Positive IHC detected inhuman gliomas tissue, human lung cancer tissue, human renal cell carcinoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

14026-1-AP targets ZEB2 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse, rat, zebrafish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ZEB2 fusion protein Ag5171
Full Name zinc finger E-box binding homeobox 2
Calculated molecular weight 136 kDa
Observed molecular weight150-170 kDa
GenBank accession numberBC060819
Gene symbol ZEB2
Gene ID (NCBI) 9839
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Zinc finger E-box-binding homeobox (ZEB2) is a key transcription factor that acts as a multifunctional regulator during nervous system development. ZEB2 contains two zinc finger domains and a homeodomain-like sequence and interacts with the TGF-ß superfamily signaling regulators, Smads, to regulate the expression of their downstream genes. ZEB2 is expressed in the developing neural tube, as well as in neural crest cells, the hippocampus and the cerebral cortex. ZEB2 has previously been implicated in EMT, cell-cycle progression, apoptosis and senescence. ZEB2 was overexpressed in bladder, ovarian, stomach, pancreatic and squamous cell carcinoma, in the intestinal subtype of stomach cancers, and at the invasive front of CRC where EMT is most prominen. ZEB2 also mediates cell-fate decision in neuronal, T cells and hematopoietic stem cells. The calculated molecular weight of ZEB2 is 136 kDa, but we find the 95 kDa band in some publication(PMID: 27659015 )


Product Specific Protocols
WB protocol for ZEB2 antibody 14026-1-APDownload protocol
IHC protocol for ZEB2 antibody 14026-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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