ChromoTek p53 N-term-Trap Agarose

p53-N-term-Trap Agarose is an affinity reagent for IP of p53. It consists of a p53 Nanobody/ VHH coupled to agarose beads, and which binds to the N-terminus of p53.

Specificity

p53

Applications

IP, CoIP

Conjugate

Agarose

Cat no : pta

Synonyms

p53 N-term-Trap, p53 Trap, p53-Trap, Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, P53, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53



Product Information

p53-N-term-Trap Agarose is an affinity reagent for IP of p53. It consists of a p53 Nanobody/ VHH coupled to agarose beads, and which binds to the N-terminus of p53.

ApplicationsIP, CoIP
ClonalityMonoclonal
HostAlpaca
Specificity/Targetp53
Species-Reactivity: Tested on human
Coupled VHHRecombinant, monoclonal anti-p53 N-term single domain antibody (sdAb) fragment
ConjugateAgarose
Beads~ 90 µm (cross-linked 4 % agarose beads)
Elution bufferSDS sample buffer
0.2 M glycine pH 2.5
Storage Buffer20% EtOH
Storage ConditionUpon receipt store at +4°C. Do not freeze!

Publications

ApplicationTitle
IP

Biochem Biophys Res Commun

Phosphorylation of p53 by LRRK2 induces microglial tumor necrosis factor α-mediated neurotoxicity.

Authors - Dong Hwan Ho
IP

Chem Biol Interact

p53 mediated transcriptional regulation of long non-coding RNA by 1-hydroxy-1-norresistomycin triggers intrinsic apoptosis in adenocarcinoma lung cancer.

Authors - Vaikundamoorthy Ramalingam
IP

Sci Rep

Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.

Authors - Karim Ullah
CoIP

J Virol

The ORF45 protein of Kaposi Sarcoma-associated Herpesvirus (KSHV) is an inhibitor of p53 signaling during viral reactivation.

Authors - Dina Alzhanova
IP

Cancers (Basel)

AML-Related NPM Mutations Drive p53 Delocalization into the Cytoplasm with Possible Impact on p53-Dependent Stress Response.

Authors - Aleš Holoubek
IP

PLoS Pathog

Novel modulators of p53-signaling encoded by unknown genes of emerging viruses.

Authors - Dina Alzhanova