Cat no : pta
p53-N-term-Trap Agarose is an affinity reagent for IP of p53. It consists of a p53 Nanobody/ VHH coupled to agarose beads, and which binds to the N-terminus of p53.
Species-Reactivity: Tested on human
|Coupled VHH||Recombinant, monoclonal anti-p53 N-term single domain antibody (sdAb) fragment|
|Beads||~ 90 µm (cross-linked 4 % agarose beads)|
|Elution buffer||SDS sample buffer|
0.2 M glycine pH 2.5
|Storage Buffer||20% EtOH|
|Storage Condition||Upon receipt store at +4°C. Do not freeze!|
Biochem Biophys Res Commun
Phosphorylation of p53 by LRRK2 induces microglial tumor necrosis factor α-mediated neurotoxicity.
Chem Biol Interact
p53 mediated transcriptional regulation of long non-coding RNA by 1-hydroxy-1-norresistomycin triggers intrinsic apoptosis in adenocarcinoma lung cancer.
Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.
Novel modulators of p53-signaling encoded by unknown genes of emerging viruses.
Antagonizing CD105 enhances radiation sensitivity in prostate cancer.
Cell Death Differ
The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation.