• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human CNTF protein


2.75-14 ng/mL

Species Reactivity




Cat no : HZ-1331


Ciliary Neurotrophic Factor

Technical Specifications

GeneID 1270
Species Human
Expression HEK293
Activity(Primary) 2.75-14 ng/mL
Purity >95%
Endotoxin<1 EU/μg
Accession NumberP26441
Molecular Mass 23-27 kDa reduced and non-reduced, monomer, non-glycosylated
Formulation 1x PBS, See Certificate of Analysis for details
Species Reactivity human

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vials to mix.


CNTF or ciliary neurotrophic factor, is a member of the IL-6 family of cytokines alongside LIF, OSM, and cardiotropin-1. It promotes gene expression, cell survival, and differentiation of sensory, ciliary, and motor neurons. It promotes rod and cone photoreceptor regeneration in response to retinal injury and degeneration. It is also thought to control B cell differentiation in the bone marrow. CNTF can be used to maintain neural stem cells in the pluripotent state, or it can promote their further differentiation into glial precursor cells, astrocytes, and oligodendrocytes (PMID: 30504707, 21912637, 26487326).


Ciliary Neurotrophic Factor



ACS Biomater Sci Eng

Electrospun PCL Nerve Conduit Filled with GelMA Gel for CNTF and IGF-1 Delivery in Promoting Sciatic Nerve Regeneration in Rat

Authors - Hailiang Xu