ATP1B2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 22338-1-AP

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Freight/Packing

Con: 51 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, human brain tissue, mouse skeletal muscle tissue

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human brain tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ATPase, Na+/K+ transporting, beta 2 polypeptide

Calculated molecular weight:
290aa,33 kDa

Observed molecular weight:
45-65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ATP1B2

Synonyms
AMOG, ATP1B2, ATPase Na+/K+ beta 2
Background

ATP1B2 is the β2 subunit of Na+/K+-ATPase which is an essential membrane-bound enzyme responsible for the transport of Na+ and K+ in most eukaryotic cells. ATP1B2 is also called the adhesion molecule on glia (AMOG) and it is highly expressed in normal glia. It is a heavily glycosylated protein that plays a role in cellular adhesion in the CNS. Recently differential expression of ATP1B2 has been found in some glioneuronal tumors (23887941, 19371356). This antibody recognizes the endogenous ATP1B2 protein in human brain. The bands between 45 kDa and 65kDa represent the glycosylated forms of ATP1B2 in different levels (8918259).


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