BRF2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12056-1-AP

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Freight/Packing

Con: 44 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HT-1080 cells, DU 145 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like

Calculated molecular weight:
47 kDa

Observed molecular weight:
50-60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BRF2

Synonyms
B related factor 2, BRF 2, BRF2, BRFU, FLJ11052, hBRFU, hTFIIIB50, TFIIIB50
Background

Human cells contain two types of RNA polymerase III transcription factor(TFIIIB), BRF1 and BRF2. BRF2,also named as BRFU, contains one TFIIB-type zinc finger. It is a general activator of RNA polymerase III transcription. It is a factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. BRF2 is recruited to type 3 promoters such as the human U6 snRNA promoter. It differs from BRF1-TFIIIB in that it contains the TFIIB-related factor BRF2 iinstead of BRF1 and its three components do not form a stable complex. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human BRF2. It recognizes a 50-60kd band in WB analysis.


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