C1S Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 14554-1-AP

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Freight/Packing

Con: 21 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human blood tissue, COLO 320 cells, human plasma tissue

Positive IHC detected in:
human liver cancer tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
complement component 1, s subcomponent

Calculated molecular weight:
77 kDa

Observed molecular weight:
88 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
C1S

Synonyms
C1 esterase, C1S, Complement C1s subcomponent, FLJ44757
Background

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r activates C1s so that it can, in turn, activate C2 and C4. C1s is a glycoprotein of approximately 88 kDa, which is activated by cleavage into an A chain and a B chain.


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