|Positive WB detected in||human plasma tissue|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Sample-dependent, check data in validation data gallery|
66268-1-Ig targets C1qC in WB applications and shows reactivity with human samples.
|Host / Isotype||Mouse / IgM|
|Immunogen||C1qC fusion protein Ag10233|
|Full Name||complement component 1, q subcomponent, C chain|
|Calculated molecular weight||245 aa, 26 kDa|
|Observed molecular weight||26 kDa|
|GenBank accession number||BC009016|
|Gene ID (NCBI)||714|
|Purification Method||Thiophilic affinity chromatograph|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
The first component of complement, C1, is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. This antibody is raised against C1qC which is the C-chain polypeptide of human complement subcomponent C1q.
Onco Targets Ther
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma.
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.