C1qC Monoclonal antibody

C1qC Monoclonal Antibody for IF, WB, ELISA

Host / Isotype

Mouse / IgM

Reactivity

human and More (1)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

CloneNo.

1C5B4

Cat no : 66268-1-Ig

Synonyms

C1Q C, C1qC, C1QG



Tested Applications

Positive WB detected inhuman plasma tissue
Positive IF detected inHUVEC cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunofluorescence (IF)IF : 1:400-1:1600
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 3 publications below

Product Information

66268-1-Ig targets C1qC in WB, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, rat
Host / Isotype Mouse / IgM
Class Monoclonal
Type Antibody
Immunogen C1qC fusion protein Ag10233
Full Name complement component 1, q subcomponent, C chain
Calculated molecular weight 245 aa, 26 kDa
Observed molecular weight 26 kDa
GenBank accession numberBC009016
Gene symbol C1QC
Gene ID (NCBI) 714
RRIDAB_2881653
Conjugate Unconjugated
Form Liquid
Purification Method Thiophilic affinity chromatograph
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The first component of complement, C1, is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. This antibody is raised against C1qC which is the C-chain polypeptide of human complement subcomponent C1q.

Protocols

Product Specific Protocols
WB protocol for C1qC antibody 66268-1-IgDownload protocol
IF protocol for C1qC antibody 66268-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Sci Rep

C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.

Authors - Anika Alberts
ratWB

J Ethnopharmacol

Network pharmacology and experimental validation-based approach to understand the effect and mechanism of Taohong Siwu Decoction against ischemic stroke.

Authors - Lingyu Pan
humanWB

Onco Targets Ther

Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma.

Authors - Hanji Huang