C1qA Polyclonal antibody

C1qA Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP,ELISA

Conjugate

Unconjugated

Cat no : 11602-1-AP

Synonyms

C1qA



Tested Applications

Positive WB detected inhuman spleen tissue, human colon tissue, human heart tissue, human liver tissue, human lung tissue, mouse liver tissue, mouse serum tissue
Positive IP detected inmouse liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 2 publications below

Product Information

11602-1-AP targets C1qA in WB, IP,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen C1qA fusion protein Ag2141
Full Name complement component 1, q subcomponent, A chain
Calculated molecular weight 245 aa, 26 kDa
Observed molecular weight 30 kDa
GenBank accession numberBC030153
Gene symbol C1QA
Gene ID (NCBI) 712
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The first component of complement, C1, is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. This antibody is raised against C1qA which is the A-chain polypeptide of human complement subcomponent C1q.

Protocols

Product Specific Protocols
WB protocol for C1qA antibody 11602-1-APDownload protocol
IP protocol for C1qA antibody 11602-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Sci Rep

C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.

Authors - Anika Alberts
mouseWB

J Neurosci

Immune quiescence of the brain is set by astroglial connexin 43.

Authors - Anne-Cécile Boulay