C4 (alpha chain) Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22233-1-AP

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Con: 37 μg/150 μl

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Species specificity:

Positive WB detected in:
human blood tissue

Positive IP detected in:
L02 cells

Positive IHC detected in:
human liver tissue

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
complement component 4A (Rodgers blood group)

Calculated molecular weight:
1744aa,193 kDa

Observed molecular weight:
95 kDa, 200 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

Acidic complement C4, C4, C4A, C4A2, C4A3, C4A4, C4A6, C4S, CO4, Complement C4 A, CPAMD2, RG

Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor and the alpha chain. This antibody raised against 1017-1336aa of human C4A protein recognize C4A alpha chain.

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