MUC1/CA15-3 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 23614-1-AP

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Con: 53 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Transfected HEK-293 cells

Positive IHC detected in:
human ovary tumor tissue, human breast cancer tissue, human ovary tumor tissue

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mucin 1, cell surface associated

Calculated molecular weight:
1264aa,123 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MUC1

Synonyms
CA15 3, CA153, CA15-3, Carcinoma associated mucin, CD227, EMA, Episialin, H23AG, KL-6, MAM6, MUC 1, MUC1, MUC1 beta, MUC1 CT, MUC1 NT, Mucin 1, Peanut reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated mucin
Background

MUC1, a type I transmembrane glycoprotein, belongs to the family of mucin proteins which are expressed by various epithelial cell types. It consists of a very large extracellular domain, a trans-membrane domain, and a short cytoplasmic tail. Among the known mucins, MUC1 is best studied and plays crucial roles in regulating many cellular properties, including cell proliferation, apoptosis, adhesion, and invasion. MUC1 primarily functions in lubrication and hydration of epithelia and protection from microbial attack. It also has been implicated in progression of numerous types of cancer.


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