CADM1 Antibody

CADM1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 14335-1-AP

Synonyms

BL2, CADM1, cell adhesion molecule 1, IGSF4, IGSF4A, Necl 2, NECL2, Nectin like protein 2, RA175, sgIGSF, ST17, sTSLC 1, SYNCAM, synCAM1, TSLC 1, TSLC1



Tested Applications

Positive WB detected inmouse liver tissue, A549 cells, human placenta tissue, mouse lung tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 3 publications below

Product Information

14335-1-AP targets CADM1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CADM1 fusion protein Ag5621
Full Name cell adhesion molecule 1
Calculated molecular weight 49 kDa
Observed molecular weight 49-60 kDa
GenBank accession number BC047021
Gene symbol CADM1
Gene ID (NCBI) 23705
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CADM1 (cell adhesion molecule 1), also referred to as SgIGSF, Necl-2 or TSLC-1, is a cell adhesion molecule belonging to the immunoglobulin superfamily. It can mediate homophilic and heterophilic cell-cell adhesion. CADM1 is expressed by a variety of cells including neurons, mast cells, spermatogonia, pancreatic islet cells, epithelial cells such as lung alveolar cells and biliary epithelial cells. CADM1 is involved in carcinoma pathogenesis and the expression of CADM1 is frequently down-regulated in various tumors derived from epithelial cells. It acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. (PMID: 18332875; 17326163; 20340131)

Protocols

Product Specific Protocols
WB protocol for CADM1 antibody 14335-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Oncol Lett

miR-214-3p promotes the proliferation, migration and invasion of osteosarcoma cells by targeting CADM1.

Authors - Haiqing Cai
humanWB

Onco Targets Ther

miR-424-5p Promotes Proliferation, Migration and Invasion of Laryngeal Squamous Cell Carcinoma.

Authors - Yujun Li
mouseWB

PLoS One

Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination.

Authors - Zhu Ying Y