CARD11 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21741-1-AP

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Freight/Packing

Con: 39 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
L02 cells

Positive IHC detected in:
human lymphoma tissue, human colon cancer tissue

Positive IF detected in:
L02 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
caspase recruitment domain family, member 11

Calculated molecular weight:
1154aa,133 kDa

Observed molecular weight:
133 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CARD11

Synonyms
BIMP3, CARD11, Carma 1, CARMA1
Background

CARD11 also named as ,BIMP3 or CARMA1, is a 1154 amino acid protein, which contains one PDZ domain, one guanylate kinase-like domain, and one CARD domain. CARD11 localizes in the cytoplasm and co-localized with DPP4 in membrane raft. CARD11 is detected in adult peripheral blood leukocytes, thymus, spleen and liver. CARD11 also is found in CARD11 promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. CARD11 is involved in the co-stimulatory signal essential for T-cell receptor mediated T-cell activation.


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