CCR2-specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 16153-1-AP

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Freight/Packing

Con: 56 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Jurkat cells, A431 cells

Positive IHC detected in:
human kidney tissue, human kidney tissue, human ovary tumor tissue

Positive FC detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
chemokine (C-C motif) receptor 2

Calculated molecular weight:
42 kDa

Observed molecular weight:
42 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CCR2

Synonyms
C C chemokine receptor type 2, C C CKR 2, CC CKR 2, CCR 2, CCR2, CCR2a, CCR2b, CD192, CKR2, CKR2A, CKR2B, CMKBR2, FLJ78302, MCP 1 R
Background

CCR2 encodes a receptor for MCP1, functioning in inflammatory processes, tumor infiltration and monocyte invasion of artery walls in atherosclerosis. There are two isoforms of CCR2, CCR2A and CCR2B. CCR2 isoforms were expressed by different cell subsets in both normal and IIM muscle. CCR2A was expressed in vessel walls and by some mononuclear cells, especially in cells involved in partial invasion in PM and IBM. CCR2B expression was observed in all satellite cells, in the muscular domain of neuromuscular junctions and in some regenerative fibers of IIM, but not in inflammatory exudates. The sequences of the two isoforms are different from 314-374 aa. This antibody 16153-1-AP is raised against the peptide of 344-358 amino acids of CCR2a. It is specicifc to CCR2a.


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