CD68 Monoclonal antibody
CD68 Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
WB, IHC, IF, ELISA
Conjugate
Unconjugated
CloneNo.
3F10E11
Cat no : 66231-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| Sample-dependent, check data in validation data gallery | |
Published Applications
| WB | See 1 publications below |
| IHC | See 4 publications below |
| IF | See 1 publications below |
Product Information
66231-1-Ig targets CD68 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CD68 fusion protein Ag22815 |
| Full Name | CD68 molecule |
| Calculated molecular weight | 37 kDa |
| GenBank accession number | BC015557 |
| Gene symbol | CD68 |
| Gene ID (NCBI) | 968 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.
Publications
| Species | Application | Title |
|---|---|---|
Lupus Intrarenal macrophage infiltration induced by T cells is associated with podocyte injury in lupus nephritis patients. | ||
Cancer Med Noncoding RNA 886 alleviates tumor cellular immunological rejection in host C57BL/C mice. | ||
Am J Cancer Res Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer. | ||
Biochem Pharmacol Glutathione S-transferases P1-mediated interleukin-6 in tumor-associated macrophages augments drug-resistance in MCF-7 breast cancer. | ||
Am J Respir Cell Mol Biol Lung Myofibroblast Promote Macrophage Pro-fibrotic Activity Through Lactate-induced Histone Lactylation. | ||
Gastroenterology NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. |
