CLIC4 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66343-1-Ig |CloneNo.: 1B7F9

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, pig, rat

Positive WB detected in:
human heart tissue, pig heart tissue, pig kidney tissue, rat kidney tissue

Positive IHC detected in:
human heart tissue, human heart tissue, human kidney tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chloride intracellular channel 4

Calculated molecular weight:
253aa,29 kDa

Observed molecular weight:
29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CLIC4

Synonyms
CLIC4, CLIC4L, DKFZp566G223, FLJ38640, H1, huH1, MTCLIC, p64H1
Background

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIC4 is a p53- and tumor necrosis factor alpha-regulated cytoplasmic and mitochondrial protein that belongs to the CLIC family of intracellular chloride channels. CLICs have actions distinct from traditional cell membrane chloride channels, including formation of ion channels in intracellular organelles and roles in membrane trafficking, apoptosis, and cell differentiation.


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