Clusterin Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12289-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human plasma tissue,

Positive IHC detected in:
human tonsillitis tissue, human breast cancer tissue, human liver cancer tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
clusterin

Calculated molecular weight:
449aa,53 kDa

Observed molecular weight:
37 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CLU

Synonyms
AAG4, Apo J, APOJ, ApoJalpha, ApoJbeta, Apolipoprotein J, CLI, CLU, clusterin, Complement cytolysis inhibitor, Ku70 binding protein 1, KUB1, NA1/NA2, SGP 2, SGP2, SP 40, TRPM 2, TRPM2
Background

Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419; 11906815). It is encoded by one single gene and cleaved posttranslationally into α (34-36 kDa) and β (36-39 kDa) subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complement (PMID: 10694874).


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