CPT1C-specific Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 12969-1-AP

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Freight/Packing

Con: 36 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, HeLa cells, rat brain tissue

Positive IP detected in:
mouse testis tissue

Positive IHC detected in:
human gliomas tissue,human testis tissue, human brain tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
carnitine palmitoyltransferase 1C

Calculated molecular weight:
792aa,90 kDa

Observed molecular weight:
70-82 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CPT1C

Synonyms
CATL1, CPT IC, CPT1 B, CPT1C, CPT1P, CPTI B, CPTIC, FLJ23809
Background

CPT1C, also named as CATL1, CPTI-B and B-CPTI, belongs to the carnitine/choline acetyltransferase family. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1C is an active forms of related brain-type carnitine palmitoyltransferase I. CPT1C may be a regulated target of malonyl-CoA that relays the “malonyl-CoA signal” in hypothalamic neurons that express the orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. (PMID: 17018521 ) This antibody specifically recognizes CPT1C, and does not cross-react with CPT1A or CPT1B.


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