CYP1B1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18505-1-AP

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Con: 56 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
MCF-7 cells, mouse heart tissue, PC-3 cells

Positive IHC detected in:
human colon cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytochrome P450, family 1, subfamily B, polypeptide 1

Calculated molecular weight:
61 kDa

Observed molecular weight:
52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CYP1B1

Synonyms
CP1B, CYP1B1, CYPIB1, Cytochrome P450 1B1, GLC3A, P4501B1
Background

Cytochrome P450 CYP1B1 is a recently cloned dioxin-inducible form of the cytochrome P450 family of xenobiotic metabolizing enzymes. CYP1B1 was found to be expressed at a high frequency in a wide range of human cancers of different histogenetic types, including cancers of the breast, colon, lung, esophagus, skin, lymph node, brain, and testis. There was no detectable immunostaining for CYP1B1 in normal tissues.(PMID:9230218). CYP1B1 is a 60 kDa protein that it also can be detected a band of 51 kDa or 57 kDa through the western blot(PMID:9525272; PMID: 9525272).


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