DIS3 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 14689-1-AP

Featured Product KD/KO validated

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat, Drosophila

Positive WB detected in:
HeLa cells, HeLa cells, human brain tissue, mouse ovary tissue, mouse testis tissue

Positive IHC detected in:
human ovary tumor tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2400
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
DIS3 mitotic control homolog (S. cerevisiae)

Calculated molecular weight:
109 kDa

Observed molecular weight:
110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DIS3

Synonyms
bA555G22.1, DIS3, dis3p, DKFZp667L1817, EXOSC11, FLJ10484, KIAA1008, Protein DIS3 homolog, RP11 342J4.3, RRP44
Background

DIS3, also named as KIAA1008 and RRP44, belongs to the ribonuclease II (RNB) family. It is a component of the exosome 3'->5' exoribonuclease complex. DIS3 is required for the 3'-processing of the 7S pre-RNA to the mature nuclear complex. It is also associated with the GTPase Ran. DIS3 has a 3'-5' exonuclease activity.


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