CRMP2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14521-1-AP

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Con: 53 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human heart tissue

Positive IHC detected in:
human colon cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
dihydropyrimidinase-like 2

Calculated molecular weight:
62 kDa

Observed molecular weight:
62 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DPYSL2

Synonyms
CRMP 2, CRMP2, DHPRP2, dihydropyrimidinase like 2, DPYSL2, DRP 2, DRP2, N2A3, ULIP 2, ULIP2, Unc 33 like phosphoprotein 2
Background

Dihydropyrimidinase-like 2 (Dpysl2), a protein involved in neuronal differentiation and axonal guidance is found altered in various nervous system diseases (PMID:19524114). It is also named as CRMP2, ULIP2 and belongs to hydantoinase/dihydropyrimidinase subfamily. The phosphorylation of the particular portion carboxyl-terminal to the basic region of DPYSL2 may play an important role in regulating its activity, and may be involved in the formation of degenerating neurites in AD brain(PMID:10757975).


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