DUSP16 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 14237-1-AP

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Freight/Packing

Con: 50 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
PC-12 cells, COLO 320 cells, HeLa cells, mouse brain tissue

Positive IHC detected in:
human colon tissue, human breast cancer tissue, human colon tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
dual specificity phosphatase 16

Calculated molecular weight:
73 kDa

Observed molecular weight:
70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DUSP16

Synonyms
DUSP16, KIAA1700, MAP kinase phosphatase 7, MKP 7, MKP7
Background

DUSP16, also known as /MKP-7, is a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. DUSP16 dephosphorylates JUN kinases (JNKs) specifically and thereby regulates T-cell differentiation, which can be responsible for the pathogenesis of Burkitt’s lymphoma and cerebral ischemia. DUSP16 was also found to induce the expression of VCAM-1 through the suppression of JNK signaling.


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