ESRP1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21045-1-AP

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Freight/Packing

Con: 42 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
COLO 320 cells, COLO 320 cells, mouse lung tissue

Positive IP detected in:
COLO 320 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
epithelial splicing regulatory protein 1

Calculated molecular weight:
681aa,76 kDa

Observed molecular weight:
76 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ESRP1

Synonyms
ESRP1, FLJ20171, RBM35A, RNA binding motif protein 35A, RNA binding protein 35A
Background

ESRP1, also named as Epithelial splicing regulatory protein 1, is a 681 amino acid protein, which belongs to the ESRP family. ESRP1 as a mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. ESRP1 specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2 and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). ESRP1 exists various isoforms and molecular weight of each isoform is 76 kDa, 67 kDa, and 73 kDa.


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