EXOC1 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 11690-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 38 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
rat brain tissue, human brain tissue, mouse brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human gliomas tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
exocyst complex component 1

Calculated molecular weight:
894aa,102 kDa

Observed molecular weight:
102 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EXOC1

Synonyms
BM 102, EXOC1, exocyst complex component 1, Exocyst complex component Sec3, FLJ10893, SEC3, SEC3L1, SEC3P
Background

EXOC1 (exocyst complex component 1), also known as SEC3, is a component of the exocyst complex which is essential for the targeting of exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex is an octameric complex that tethers vesicles at the plasma membrane, regulates polarized exocytosis, and recruits membranes and proteins required for nanotube formation.Recently it has been reported that exocyst complex proteins are likely a key effector of Nef-mediated enhancement of nanotube formation, and possibly microvesicle secretion, which suggests a new paradigm of exocyst involvement in polarized targeting for intercellular transfer of viral proteins and viruses.


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