FGL2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11827-1-AP

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Freight/Packing

Con: 27 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human ileum tissue, mouse thymus tissue

Positive IHC detected in:
human colon cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
fibrinogen-like 2

Calculated molecular weight:
50 kDa

Observed molecular weight:
70 kDa,50-60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FGL2

Synonyms
FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49
Background

FGL2, also known as fibroleukina, is secreted by T lymphocytes, constitutively expressed in cytotoxic T cells. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites. It is migrated as a 70kd band in western blotting analysis.


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