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  • KD/KO Validated

FKBP1A Polyclonal antibody

FKBP1A Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 10273-1-AP

Synonyms

12 kDa FK506 binding protein, 12 kDa FKBP, FK506 binding protein 1A, FKBP 12, FKBP 1A, FKBP1, FKBP12, FKBP12C, FKBP1A, Immunophilin FKBP12, PKC12, PKCI2, PPIASE, PPIase FKBP1A, Rotamase



Tested Applications

Positive WB detected inmouse brain tissue, human heart tissue
Positive IHC detected inhuman ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

10273-1-AP targets FKBP1A in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FKBP1A fusion protein Ag0406
Full Name FK506 binding protein 1A, 12kDa
Calculated molecular weight 12 kDa
Observed molecular weight 12-16 kDa
GenBank accession numberBC001925
Gene symbol FKBP1A
Gene ID (NCBI) 2280
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

FKBP1A(FK506-binding protein 1A) is also named as FKBP1, FKBP12 and belongs to the FKBP-type PPIase family.It keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Protocols

Product Specific Protocols
WB protocol for FKBP1A antibody 10273-1-APDownload protocol
IHC protocol for FKBP1A antibody 10273-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Mol Pharmacol

FK506 Binding Protein 12 Modulates μ Opioid Receptor Phosphorylation and PKC{epsilon}-dependent Signaling by its Direct Interaction with the Receptor.

Authors - Qiu Yu Y
  • KD Validated
humanWB

Oncotarget

TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast.

Authors - Xiaodan Hou
humanWB

Cell Rep

Sequencing of captive target transcripts identifies the network of regulated genes and functions of primate-specific miR-522.

Authors - Shen Mynn Tan