FUT4 Antibody 12 Publications

Rabbit Polyclonal| Catalog number: 19497-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HeLa cells,Jurkat cells, NIH/3T3 cells, HepG2 cells, HL-60 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human lung cancer tissue, human gliomas tissue, human lung cancer tissue, human skin cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)

Calculated molecular weight:
59 kDa

Observed molecular weight:
95-110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FUT4

Synonyms
Alpha (1,3) fucosyltransferase, CD15, ELFT, FCT3A, FUC TIV, Fucosyltransferase 4, Fucosyltransferase IV, FucT IV, FUT4, FUTIV, SSEA 1, SSEA1
Background

FUT4,also named as CD15, SSEA-1ELFT and FCT3A, belongs to the glycosyltransferase 10 family. FUT4 may catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens. FUT4 is Stage-specific embryonic antigen-1 (SSEA-1), an antigenic epitope defined as a Lewis X carbohydrate structure is expressed on murine embryonal carcinoma cells (EC), murine ES and iPS cells, and murine and human germ cells. It is widely used as a positive surface marker for mouse undifferentiated ES and iPS cells and a negative surface marker for human undifferentiated ES and iPS cells. Expression is down-regulated following differentiation of murine EC and ES cells, while the differentiation of human EC and ES cells is accompanied by an increase in FUT4 expression. FUT4 is associated with cell adhesion, migration and differentiation.


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