FXYD2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11198-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, HEK-293 cells, human kidney tissue, human liver tissue, human skeletal muscle tissue, mouse skeletal muscle tissue

Positive IHC detected in:
human pancreas cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
FXYD domain containing ion transport regulator 2

Calculated molecular weight:
7 kDa

Observed molecular weight:
7 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FXYD2

Synonyms
ATP1C, ATP1G1, FXYD2, HOMG2, Sodium pump gamma chain
Background

FXYD2 (FXYD domain-containing ion transport regulator 2), also known as the gamma-subunit of the NaK-ATPase, belongs to the FXYD family which has been proposed to be the regulators of Na, K-ATPase function by lowering affinities of the system for potassium and sodium. The expression of FXYD2 is most abundant in kidney, while it is also detected in several other tissues like placenta, pancreas, and dorsal root ganglia (DRGs). Three splice variants of FXYD2 have been reported in mouse kidney, namely FXYD2 γa, -γb,and -γc. FXYD2 γa has been identified as a pancreatic beta cell-specific biomarker. This antibody can recognize all three isoforms of FXYD2.


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