GJB3 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 12880-1-AP

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Freight/Packing

Con: 36 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat, marmosets

Positive WB detected in:
mouse ovary tissue, HeLa cells, human brain tissue, human heart tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human cervix tissue, human cervix tissue, human ovary tumor tissue, human skin cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
gap junction protein, beta 3, 31kDa

Calculated molecular weight:
270aa,31 kDa

Observed molecular weight:
31 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GJB3

Synonyms
Connexin 31, CX31, DFNA2, DFNA2B, EKV, FLJ22486, Gap junction beta 3 protein, GJB3
Background

GJB3, also known as Connexin-31 (Cx31), belongs to the connexin family. Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. Mutations in the gene of GJB3 have been described in patients with dominant and recessive hearing impairment and in patients with erythrokeratodermia variabilis (EKV).


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