GLRX2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 13381-1-AP

Featured Product KD/KO validated

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Con: 56 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A549 cells, human heart tissue, mouse heart tissue

Positive IF detected in:
A549 cells

Recommended dilution:
WB : 1:200-1:1000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glutaredoxin 2

Calculated molecular weight:
164aa,18 kDa

Observed molecular weight:
16 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GLRX2

Synonyms
bA101E13.1, GLRX2, Glutaredoxin 2, Glutaredoxin 2, mitochondrial, GRX2
Background

GLRX2(Glutaredoxin-2) is also named as GRX2 and belongs to the glutaredoxin family. It facilitates the maintenance of cellular redox homeostasis upon treatment with apoptotic agents, thereby preventing cardiolipin oxidation and cytochrome C release. The GLRX2, which exists in a dynamic equilibrium of enzymatically active monomers and quiescent dimers,is a 16-kDa protein directed either to the nucleus or to the mitochondria through differential splicing of the first exon(PMID: 17121859). It has 2 isoforms produced by alternative splicing.


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