IFT88 Antibody 122 Publications

Rabbit Polyclonal| Catalog number: 13967-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 40 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat, dog, chicken, zebrafish

Positive WB detected in:
HEK-293 cells, A549 cells, HepG2 cells, Jurkat cells, K-562 cells, mouse brain tissue, mouse eye tissue, mouse kidney tissue, mouse testis tissue, mouse thymus tissue, NIH/3T3 cells

Positive IP detected in:
knockout cells and WT cells, HEK-293 cells

Positive IHC detected in:
human heart tissue, human heart tissue, human pancreas tissue

Positive IF detected in:
MDCK cells, hTERT-RPE1 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
intraflagellar transport 88 homolog (Chlamydomonas)

Calculated molecular weight:
94 kDa

Observed molecular weight:
88-95 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IFT88

Synonyms
IFT88, TPR repeat protein 10, TTC10
Background

Intraflagellar transport (IFT), mediated by molecular motors and IFT particles, is an important transport process that occurs in the cilium and has been shown to be essential for the assembly and maintenance of cilia and flagella in many organisms. IFT88 (intraflagellar transport protein 88; also known as TG737 or TTC10) is a component of IFT particles and required for cilium biogenesis. Defects in IFT88/Tg737 lead to polycystic kidney disease (11062270). IFT88 localizes to spindle poles during mitosis and is required for spindle orientation in mitosis (21441926). This antibody was raised against the C-terminal region of human IFT88 and can detect the endogenous level of IFT88.


Back
to top