IGF1A-Specific Antibody 12 Publications

Rabbit Polyclonal| Catalog number: 20214-1-AP

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Freight/Packing

Con: 57 μg/150 μl

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Species specificity:
human, mouse, pig, rat

Positive WB detected in:
mouse testis tissue, L02 cells, mouse liver tissue, mouse ovary tissue, mouse uterus tissue, PC-3 cells

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human liver tissue, human liver tissue, human liver cancer tissue

Positive IF detected in:
HepG2 cells, HeLa cells, HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
insulin-like growth factor 1 (somatomedin C)

Calculated molecular weight:
17 kDa

Observed molecular weight:
15-20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IGF1

Synonyms
IBP1, IGF I, IGF1, IGF1A, IGF1B, IGFI, Insulin like growth factor I, Mechano growth factor, MGF, Somatomedin C
Background

IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF-1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF-1A.


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