Pre-IL18 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60070-1-Ig |CloneNo.: 5C6F8

Featured Product KD/KO validated

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, hamster

Positive WB detected in:
HeLa cells, HepG2 cells

Positive IF detected in:
MCF-7 cells, Hela cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:10-1:100

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgG2b

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 18 (interferon-gamma-inducing factor)

Calculated molecular weight:
193aa,22 kDa

Observed molecular weight:
24 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL18

Synonyms
Iboctadekin, IFN gamma inducing factor, IGIF, IL 1 gamma, IL 18, IL 1g, IL18, IL1F4, Interleukin 1 gamma, Interleukin 18
Background

IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form.


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