|Positive WB detected in||Hepg2 cells|
|Positive IF detected in||HeLa cells|
|Positive FC detected in||HepG2 cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
The 60206-1-Ig immunogen is Fusion Protein IL-7 protein expressed in E. coli.
|Host / Isotype||Mouse / IgG2b|
|Immunogen||IL-7 fusion protein Ag16314|
|Full Name||interleukin 7|
|Calculated molecular weight||20 kDa|
|Observed molecular weight||17 kDa|
|GenBank accession number||BC047698|
|Gene ID (NCBI)||3574|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Interleukin-7 (IL7) is a cytokine mportant for B and T cell development. IL7 plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes. It is also a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Furthermore, IL7 can improve the antiviral function and expansion of natural killer (NK) cells and regulate the development and differentiation of dendritic cells. IL7 has also been reported as a regulator of the development of central nervous system and myogenesis and skeletal muscle cell migration.
Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial-Mesenchymal Transition.
Free Radic Biol Med
Oxidative stress-induced IL-15 transtrans-presentation in keratinocytes contributes to CD8+ T cells activation via JAK-STAT pathway in vitiligo.