Insulin Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66198-1-Ig |CloneNo.: 4B6A7

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Freight/Packing

Con: 185 μg/150 μl

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Species specificity:
human, mouse

Positive IHC detected in:
human pancreas tissue, human pancreas tissue, mouse pancreas tissue

Recommended dilution:
IHC : 1:500-1:5000

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
insulin

Calculated molecular weight:
110aa,12 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
INS

Synonyms
ILPR, INS, Insulin, IRDN
Background

Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.


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