KIR3DL1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13335-1-AP

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Freight/Packing

Con: 35 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human liver tissue

Positive FC detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1

Calculated molecular weight:
444aa,49 kDa

Observed molecular weight:
49 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KIR3DL1

Synonyms
CD158E, CD158E1, KIR, KIR3DL1, MHC class I NK cell receptor, NKAT 3, NKAT3, NKB1, NKB1B, p70 NK receptor CL 2/CL 11
Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous. This antibody is raised against 22-344 amino acids of human KIR3DL1 and recognizes both KIR3DL1 (49 kDa) and KIR3DS1 (43 kDa).


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