KMO Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 10698-1-AP

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Freight/Packing

Con: 39 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse heart tissue, HeLa cells, mouse spleen tissue, rat spleen tissue

Positive IHC detected in:
mouse heart tissue, human breast cancer tissue, human prostate cancer tissue, mouse heart tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

Calculated molecular weight:
55.8 kDa

Observed molecular weight:
55.8 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KMO

Synonyms
dJ317G22.1, KMO, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase
Background

KMO(Kynurenine 3-monooxygenase) is an NADPH-dependent flavin monooxygenase, catalysing the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine. KMO is a membrane protein located on the outer membrane of mitochondria. Tissue distribution studies have revealed that, in rats, highest enzyme activity is found in kidney and liver, with brain having the least activity in comparison to peripheral organs(PMID: 9237672).


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