Importin beta Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10077-1-AP

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Freight/Packing

Con: 22 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, A2780 cells, HeLa cells, HT-1080 cells, rat brain tissue

Positive IHC detected in:
human colon cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
karyopherin (importin) beta 1

Calculated molecular weight:
97 kDa

Observed molecular weight:
90-97 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KPNB1

Synonyms
IMB1, Impnb, Importin 90, Importin subunit beta 1, IPO1, IPOB, karyopherin (importin) beta 1, Karyopherin subunit beta 1, KPNB1, NTF97, Nuclear factor p97, PTAC97
Background

Importin beta1, also known karyopherin beta or KPNB1, is a nuclear transport receptor that plays a key role in the nuclear import process. Importin beta1 and importin alpha work in concert to transport cargo into the nucleus, functioning as an essential component of the classical nuclear localization signal (NLS) pathway. Elevated expression of importin beta1 has been found in cervical tumors. (22125623)


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