LRPPRC Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 21175-1-AP

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 25 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
HepG2 cells, HeLa cells, mouse heart tissue, mouse kidney tissue, mouse liver tissue, mouse skeletal muscle tissue, rat kidney tissue, rat liver tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human heart tissue, human kidney tissue

Positive IF detected in:
HepG2 cells, HEK-293 cells, Hela cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
leucine-rich PPR-motif containing

Calculated molecular weight:
1394aa,158 kDa

Observed molecular weight:
130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LRPPRC

Synonyms
130 kDa leucine rich protein, CLONE 23970, GP130, LRP 130, LRP130, LRPPRC, LSFC
Background

LRPPRC (also called LRP130 or GP130) is a 130-kDa RNA-binding protein of the pentatricopeptide repeat family. LRPPRC localizes primarily to the mitochondria where it binds to poly(A) mRNA. It plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. LRPPRC has also been shown to regulate nuclear gene transcription and to bind specific RNA molecules in both the nucleus and the cytoplasm. Mutations in LRPPRC gene are associated with the French-Canadian type of Leigh syndrome.


Back
to top