Myelin basic protein Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 10458-1-AP

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Con: 75 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue

Positive IHC detected in:
human brain tissue, human brain tissue, human gliomas tissue

Recommended dilution:
WB : 1:1000-1:6000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
myelin basic protein

Calculated molecular weight:
33 kDa

Observed molecular weight:
17-22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MBP

Synonyms
MBP, Myelin A1 protein, Myelin basic protein
Background

MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.


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