ME2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 24944-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human

Positive WB detected in:
K-562 cells, HeLa cells, HL-60 cells, Jurkat cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human pancreas cancer tissue, human colon tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:100-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
malic enzyme 2, NAD(+)-dependent, mitochondrial

Calculated molecular weight:
65 kDa

Observed molecular weight:
54 kDa, 65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ME2

Synonyms
Malic enzyme 2, ME2, NAD ME
Background

ME2(malic enzyme 2) is also named as NAD-ME and belongs to the malic enzymes family. ME1, ME2 are important for NADPH production, lipogenesis and glutamine metabolism, but ME2 has a more profound effect. ME2 is a genome-coded mitochondrial enzyme that converts malate to pyruvate and is involved in neuronal synthesis of the neurotransmitter γ-aminobutyric acid (GABA)(PMID:15532013). This protein has 2 isoforms produced by alternative splicing with the MW of 65 kDa and 54 kDa.


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