MUC16,CA125 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60261-1-Ig |CloneNo.: 2B11B10

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Freight/Packing

Con: 105 μg/150 μl

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Species specificity:
human

Positive IHC detected in:
human ovary tumor tissue

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
mucin 16, cell surface associated

Calculated molecular weight:
2353 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MUC16

Synonyms
CA 125, CA125, FLJ14303, MUC 16, MUC16, Mucin 16
Background

MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.


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