NCOA5 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 20175-1-AP

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Con: 46 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, HeLa cells

Positive IP detected in:
HEK-293 cells

Positive IF detected in:
Hela cells

Positive FC detected in:
HEK-293 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
nuclear receptor coactivator 5

Calculated molecular weight:
579aa,66 kDa

Observed molecular weight:
66 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NCOA5

Synonyms
bA465L10.6, CIA, KIAA1637, NCoA 5, NCOA5, nuclear receptor coactivator 5
Background

Nuclear receptor coactivator 5 (NCOA5), also known as coactivator independent of AF-2 (CIA), possesses both repressor and activator functions (PMID: 11113208). It can interact with Estrogen Receptor (ER) alpha and ER beta in a ligand-dependent manner. NCOA5 has been shown to regulate the ER alpha-mediated transcription as well as the expression of the c-Myc gene (PMID: 11113208; 15073177). Recently identified as a conserved component of pluripotent stem cells, mammalian NCOA5 may contribute to the maintenance of the pluripotent stem cell population (PMID: 24268775).


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