NPL Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 16715-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse kidney tissue, Raji cells

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:1000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)

Calculated molecular weight:
27 kDa;35 kDa

Observed molecular weight:
35 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NPL

Synonyms
c112, C1orf13, N acetylneuraminate lyase, NALase, NPL, Sialate lyase, Sialate pyruvate lyase, Sialic acid aldolase, Sialic acid lyase
Background

The N-acetylneuraminate lyase(NPL) from human (hNAL) which consists of 320 amino acids, has a molecular mass of 35.2 kDa and it catalyses the reversible aldol reaction of sialic acid, and has been extensively used in the synthesis of sialic acids and its analogues(PMID:19057931). The enzyme is widely distributed and are present in numerous pro- and eukaryotic cells, in which they are localized only in the cytosol(PMID:12453637). It belongs to the DHDPS family and has 5 isoforms produced by alternative splicing.


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