Occludin Antibody 29 Publications

Rabbit Polyclonal| Catalog number: 13409-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells,mouse liver tissue, human liver tissue, human kidney tissue, mouse kidney tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human breast cancer tissue

Positive IF detected in:
A431 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:800
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
occludin

Calculated molecular weight:
522aa,59 kDa

Observed molecular weight:
59 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
OCLN

Synonyms
occludin, OCLN
Background

Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains, intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms, owing to modifications at the posttranscriptional and posttranslational levels (PMID: 22083955).


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