PDE6A Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 21200-1-AP

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Con: 28 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, mouse eye tissue

Positive IHC detected in:
human ovary tumor tissue, human colon cancer tissue, human ovary tumor tissue

Positive IF detected in:
retinal tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : N/A

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphodiesterase 6A, cGMP-specific, rod, alpha

Calculated molecular weight:
860aa,100 kDa

Observed molecular weight:
100-110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PDE6A

Synonyms
CGPR A, GMP PDE alpha, PDE V B1, PDE6 alpha, PDE6A, PDEA
Background

PDE6A(Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) is also named as GMP-PDE alpha, PDE V-B1, PDEA and belongs to the cyclic nucleotide phosphodiesterase family. PDE6A contains an open reading frame capable of coding for a polypeptide of 859 amino acids and about 100 kDa. It is a subunit of a key phototransduction enzyme which participates in processes of transmission and amplification of the visual signal. The expression of PDE6 alpha in retina is essential for normal expression of PDE6 beta and PDE6 gama.


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