PDLIM1/CLP36 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 11674-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 90 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse lung tissue, human ileum tissue, human lung tissue, mouse heart tissue

Positive IP detected in:
mouse heart tissue

Positive IHC detected in:
human pancreas cancer tissue

Positive IF detected in:
MCF-7 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
PDZ and LIM domain 1

Calculated molecular weight:
329aa,36 kDa

Observed molecular weight:
36 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PDLIM1

Synonyms
CLIM1, CLP 36, CLP36, Elfin, hCLIM1, LIM domain protein CLP 36, PDLIM1, PDZ and LIM domain 1, PDZ and LIM domain protein 1
Background

PDLIM1, also named as CLIM1, CLP-36, CLP36, hCLIM1 and Elfin, is a member of the actinin-associated LIM protein (ALP)/enigma protein family, plays a role in neurite outgrowth in the peripheral nervous system. It is a cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton. PDLIM1 and PALLD formed a complex in the dorsal root ganglion (DRG) and PDLIM1 and PALLD were colocalized in the neurites and cell bodies of primary DRG neurons. PDLIM1 may interact with PALLD to influence neurite outgrowth during sciatic nerve regeneration. (PMID: 20381583)


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